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Updated: Sep 30, 2026

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Implantation of biventricular assist devices for chronic heart transplant rejection
Akira Sezai1, Latif Arusoglu, Kazutomo Minami
1Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine-Westphalia, Ruhr University of Bochum, Bad Oeynhausen, Germany. akisez@eagle.ocn.ne.jp
Abstract:
Mechanical circulatory support has been used to treat graft failure caused by rejection after heart transplantation, but the prognosis remains bleak. Organ failure induced by the addition of or an increase in immunosuppressive medication is known to be a cause of the poor outcomes. Thus we tried a new therapeutic technique that allows complete withdrawal of immunosuppressive medication, as the donor heart is removed and circulatory support is maintained with a biventricular assist device.

