Is the practice of paediatric inpatient medicine evidence-based?

V A Moyer1, A K Gist, E J Elliott

  • 1Center for Clinical Research and Evidence Based Medicine, University of Texas-Houston Medical School, Houston, Texas 77030, USA. virginia.a.moyer@uth.tmc.edu

Insights

Most pediatric inpatient treatments are supported by high-level evidence (Level I or II). However, evidence is lacking for patients admitted solely for observation or evaluation.

Area of Science:

  • Pediatric Medicine
  • Evidence-Based Practice
  • Healthcare Management

Background:

  • General pediatric units manage a wide range of patient conditions.
  • Assessing the evidence base for clinical interventions is crucial for quality patient care.
  • Previous studies have highlighted variability in evidence-based practice across different medical specialties.

Purpose of the Study:

  • To evaluate the level of evidence supporting primary interventions for pediatric inpatients in general units.
  • To determine the proportion of pediatric admissions managed with high-level evidence-based treatments.

Main Methods:

  • A retrospective review of 142 pediatric admissions across two general units in the USA and Australia.
  • Identification of primary diagnosis and treatment for each patient.
  • Literature review to ascertain the evidence level (Level I, II, or III) supporting each intervention.

Main Results:

  • High-level evidence (Level I or II) supported primary interventions in 75% of pediatric admissions.
  • Level I evidence (randomized trials) supported 31% of interventions, while Level II evidence supported 44%.
  • A significant portion (24%) of patients were admitted for observation/evaluation without specific therapeutic interventions.

Conclusions:

  • The majority of primary interventions for pediatric inpatients are supported by robust scientific evidence.
  • A notable number of admissions are for observation, lacking clear evidence-based justification for intervention.
  • Further research is needed to establish evidence-based guidelines for observation and evaluation admissions in pediatrics.
Abstract

Related Concept Videos

Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in hospitals have...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Patient-centered Care01:13

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...