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Updated: Jul 24, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Dermatitis caused by physical irritants
R Morris-Jones1, S J Robertson, J S Ross
1St John's Institute of Dermatology Contact Dermatitis Clinic, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK. themojos@cwcom.net
Background:
Although physical irritant contact dermatitis (PICD) is a common occupational dermatosis, it is one of the least well understood because of its multiple types, lack of diagnostic test, and the many mechanisms involved in its production.
Objectives:
To characterize the materials and mechanisms of physical irritation of the skin.
Methods:
We did a retrospective analysis over the past 20 years of all patients with a diagnosis of PICD at St John's Institute of Dermatology Contact Dermatitis Clinic.
Results:
Of the 29,000 patients who attended the clinic over the study period, 392 patients were diagnosed with PICD and of these, 335 files were analysed.
Conclusions:
Our findings show that PICD accounted for 1.15% of all patients attending the contact clinic over the study period. Diverse occupations and materials were implicated. The most common cause of PICD was low humidity due to air-conditioning, which caused dermatitis of the face and neck in office workers due to drying out of the skin.
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