[A clinico-immunologic study of epileptic children and adolescents and their relatives]

The presentation is concerned with a study of immunological shifts in epileptic children and in their relatives. These changes were detected with the aid of a complement fixation test in the blood serum of 5 epileptic patients and 103 relatives. It was established that in epileptic patients the brain autoantigens were found in 30,8% of the cases, the antibrain antibodies in 7.7%. There was no correlation between the frequency of the detected brain antigens in the blood serum of the sick children, the sex, duration of the disease, hereditary loading and the genesis of epilepsy. Autoimmune shifts were seen in 28.15% of the cases in the blood of the relatives. Autoimmune shifts were found in the families of such children with autoimmune changes in 52.9% while among the relatives -- without autoimmune changes in 15.9% of the cases.