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Related Experiment Videos

Protein C deficiency. Biatrial thrombus presentation.

Akram A Saleh1

  • 1Department of Cardiology, Medical College, Jordan University of Science and Technology, PO Box 3030, Irbid, Jordan.

Saudi Medical Journal
|August 14, 2002
PubMed
Summary

Protein C deficiency, a genetic clotting disorder, can cause blood clots. This case study shows a rare instance of biatrial thrombus, successfully treated with anticoagulation therapy.

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Area of Science:

  • Cardiology
  • Hematology
  • Genetics

Background:

  • Protein C deficiency is an inherited thrombophilia.
  • It commonly presents as venous thrombosis in adults.
  • Biatrial thrombus is an unusual manifestation.

Observation:

  • A male patient presented with dyspnea and recurrent dizziness.
  • These symptoms were associated with a biatrial thrombus.
  • The patient had a diagnosed protein C deficiency.

Findings:

  • The patient's symptoms and biatrial thrombus resolved completely.
  • Resolution occurred within three weeks of starting anticoagulation.
  • This highlights a rare but treatable presentation of protein C deficiency.

Implications:

  • This case expands the known clinical presentations of protein C deficiency.
  • It underscores the importance of considering thrombophilia in patients with unexplained thrombi.
  • Anticoagulation appears effective for managing biatrial thrombi in protein C deficiency.

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