Granulation tissue formation in oophorectomized rats treated with female sex hormones. I. A histological study

Granulation tissue formation was studied in experimental granulomas up to three weeks in oophorectomized rats treated with female sex hormones. The influence of estrogen and progesterone during the early phase of healing could sucessfully be followed histologically. The amount of DNA and hemoglobin in the granulomas correlated well with the amount of cells and the capillary bed found in the histological sections.