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Waisman Center.

Marsha Mailick Seltzer1

  • 1University of Wisconsin-Madison, Madison, WI 53705 2280, USA. mseltzer@waisman.wisc.edu

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
|August 15, 2002
PubMed
Summary

The Waisman Center supports research on human development, neurodegenerative diseases, and developmental disabilities. Studies examine gene expression, language disorders, visual attention, and early intervention effects.

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Area of Science:

  • Behavioral science
  • Social science
  • Biomedical research
  • Human development
  • Developmental disabilities
  • Neurodegenerative diseases

Background:

  • The Waisman Center Motor Research and Developmental Disabilities Research Center (MRDDRC) facilitates interdisciplinary research.
  • Research spans human development, developmental disabilities, and neurodegenerative diseases.

Purpose of the Study:

  • To provide an overview of research supported by the Waisman Center MRDDRC.
  • To highlight key research areas and examples across four specialized units.

Main Methods:

  • Molecular and Genetic Sciences Unit: Investigating gene expression abnormalities in Down syndrome neuronal stem and progenitor cells.
  • Communication Processes Unit: Studying language disorders in adolescents with Down syndrome and Fragile X syndrome.
  • Sensory and Cognitive Processes Unit: Examining the development of selective visual attention in early infancy.
  • Social and Affective Processes Unit: Analyzing long-term effects of early intervention on educational and social outcomes.

Main Results:

  • Abnormalities in gene expression identified in Down syndrome neural cells.
  • Language disorders are prevalent in adolescents with Down syndrome and Fragile X syndrome.
  • Selective visual attention develops within the first six months of life.
  • Early intervention shows long-range positive effects on education and behavior.

Conclusions:

  • The Waisman Center MRDDRC fosters diverse research critical to understanding human development and disabilities.
  • Research findings contribute to knowledge in genetics, communication, cognition, and social-affective development.
  • Interdisciplinary approaches are essential for addressing complex developmental and neurodegenerative conditions.

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