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Regulatory T cells induced by allochimeric major histocompatability class I therapy inhibit allograft apoptosis

N Semiletova1, X D Shen, F Gao

  • 1The Dumont-UCLA Transplant Center, University of California-Los Angeles, 10833 LeConte Avenue, Los Angeles, CA 90095-7054, USA.

Transplantation Proceedings
|August 15, 2002
PubMed
Abstract

No abstract available in PubMed .

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

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