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Extraendometrial mullerian adenosarcoma.

J A Toral

Philippine Journal of Obstetrics & Gynecology : Official Publication, Philippine Obstetrical and Gynecological Society

|August 15, 2002

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This case report details a rare mullerian adenocarcinoma found in the cervix, ovary, and peritoneum, initially misdiagnosed as endometriosis. The study discusses diagnosis, management, and recurrence of this unusual gynecologic malignancy.

Area of Science:

Gynecologic Oncology
Pathology

Background:

Mullerian adenocarcinoma is a rare malignancy originating from the female reproductive tract.
This report focuses on an unusual presentation involving multiple sites without endometrial involvement.

Observation:

A 38-year-old patient presented with vaginal bleeding and cervical masses, initially misdiagnosed as endometriosis.
Laparotomy revealed masses in the vesico-uterine space, cul-de-sac, and ovarian involvement.
Microscopic examination confirmed benign glandular and malignant stromal elements.

Findings:

The tumor involved the cervix, pelvic peritoneum, and ovary, with no endometrial involvement.
Postoperative radiotherapy was administered, followed by chemotherapy for recurrent disease.
Recurrences were noted in the pelvis and vagina within 4 months.

Keywords:

Adnexal Effects--etiology Biology Case Studies Diseases Examinations And Diagnoses Genital Effects, Female Genitalia Genitalia, Female Neoplasms--etiology Physiology Research Methodology Studies Treatment Urogenital System

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Implications:

Highlights diagnostic challenges in distinguishing rare gynecologic malignancies from benign conditions.
Underscores the importance of thorough pathological examination for accurate diagnosis.
Discusses management strategies, prognostic factors, and recurrence patterns for this rare tumor.