Related Experiment Video

Updated: Sep 30, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

[Antibodies seroprevalence for mycoplasma pneumoniae antigens in patients with bronchial asthma]

Daniela Friedek1, Alicja Ekiel, Patryk Szulakowski

  • 1Katedry i Zakładu Mikrobiologii, Slaskiej Akademii Medycznej w Katowicach.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|August 17, 2002
PubMed

Insights

Mycoplasma pneumoniae infections are more common in bronchial asthma patients than healthy individuals. Early diagnosis and antibiotic treatment can help manage asthma exacerbations and reduce corticosteroid use.

Area of Science:

  • Respiratory Medicine
  • Infectious Diseases
  • Immunology

Context:

  • Respiratory infections, including those caused by atypical bacteria like Mycoplasma pneumoniae, are implicated in the development and exacerbation of bronchial asthma.
  • Mycoplasma pneumoniae is a suspected contributor to asthma initiation and worsening.

Purpose:

  • To investigate the prevalence of anti-Mycoplasma pneumoniae antibodies in patients with bronchial asthma compared to a healthy control group.
  • To assess the frequency of Mycoplasma pneumoniae infection markers in asthma patients.

Summary:

  • The study utilized the immunoenzymatic assay (ELISA) to detect IgG, IgM, and IgA class antibodies against Mycoplasma pneumoniae.
  • Serological markers of Mycoplasma pneumoniae infection were found in 15% of bronchial asthma patients, versus 5.13% in the control group.
  • This indicates a higher occurrence of Mycoplasma pneumoniae infection in individuals with bronchial asthma.

Impact:

  • Diagnosing Mycoplasma pneumoniae infection in bronchial asthma patients is crucial for effective management.
  • Appropriate antibiotic therapy targeting Mycoplasma pneumoniae can resolve bronchial hyperreactivity, potentially reducing the need for inhaled corticosteroids.
  • Rapid and precise immunoenzymatic assays for specific antibodies aid in timely diagnosis and treatment decisions.

Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...