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[Evaluation of effects of L-thyroxine therapy in differentiated thyroid carcinoma on the cardiovascular system
G Matuszewska1, J Roskosz, J Włoch
1Zakładu Medycyny Nuklearnej i Endokrynologii Onkologicznej Centrum Onkologii-Instytut im. M. Skłodowskiej-Curie, Oddział w Gliwicach.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|August 17, 2002
Abstract:
Patients with differentiated thyroid carcinoma are treated by thyreoidectomy, followed by radioiodine treatment. A life-time suppressive therapy with L-thyroxine is also indicated. However, it may cause cardiovascular side effects. The aim of the study was a prospective evaluation of the left ventricle hypertrophy in patients treated with suppressive doses of thyroxine. A significant rise in left ventricular mass and mass index was noted during the first year of therapy and could be prevented by a simultaneous treatment with low doses of bisoprolol.