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Updated: Sep 29, 2026

Bone Marrow-derived Macrophage Production
07:06

Bone Marrow-derived Macrophage Production

Published on: November 22, 2013

Shiga toxin 2 induces macrophage-granulocyte colonies from human bone marrow and cord blood stem cells

Shin Chiyoda1, Tae Takeda, Yosuke Aoki

  • 1Nagasaki Red Cross Blood Center, Nagasaki, Japan.

Infection and Immunity
|August 17, 2002
PubMed

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...