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[Some aspects of pharmacotherapy among the eldest living in veterans' homes]

Jacek Sein Anand1, Zygmunt Chodorowski

  • 1I Klinika Chorób Wewnetrznych i Ostrych Zatruć Akademii Medycznej, 80-211 Gdańsk, ul. Debinki 7.

Przeglad Lekarski
|August 20, 2002
PubMed

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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