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Overview of tumor lysis syndrome
1University of Tennessee Medical Center, University of Tennessee College of Nursing, 1924 Alcoa Hwy, Box 104, Knoxville, TN 37920, USA.
Objectives:
To provide a general overview of tumor lysis syndrome (TLS) focusing on the incidence, epidemiology, and patient outcomes associated with the syndrome; review the role of the oncology nurse in impacting patient outcomes and identify evolving issues relating to TLS.
Data Sources:
Primary and tertiary literature related to TLS and clinical practice experience.
Conclusions:
Issues related to TLS continue to evolve and the oncology nurse plays a key role in patient management. As with other neoplastic disease-related complications (e.g., pain, nausea/vomiting), knowledge of TLS and attention and intervention, where appropriate, can positively impact patient outcome.
Implications For Nursing Practice:
The oncology nurse plays a critical role in impacting patient outcomes with respect to TLS ranging from collaboration with other disciplines to identifying patients at risk, through assessments, vigilant monitoring, and implementing optimal treatment regimens.