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Lebanese population: prevalence of the erythrocyte phenotypes
E M Baz1, R A Mahfouz, R S Tabarani
1Dept of Pathology, American University of Beirut, Lebanon. ek01@aub.edu.lb
Study Objectives:
This survey was designed to be a descriptive study of the erythrocyte phenotype prevalence in Lebanon. The general aim was to provide transfusion centers and blood banks with the occurrence of the nation's erythrocyte phenotypes in the population they are serving. The results were descriptively compared to Caucasians.
Subjects And Methods:
632 blood samples were collected from the Lebanese population in the 5 muhafazats (regions). Of which, 350 samples were extensively phenotyped for the blood group systems ABO, Kell, Kidd, Duffy, MNS, Lewis, Lutheran and P; and 282 samples were selectively phenotyped for Fy(a), Fy(b) and Kp(a). Additionally, 3064 random blood donors were studied for the ABO and D blood groups.
Main Results:
With respect to the blood group phenotypes, the Lebanese are similar to the Caucasian population with the exception of rr, Le(b), Le (a-b-), Fy (a-b-), M+N+S-s+ and M-N-S-s+.
Conclusion:
It is of scientific cognizance and interest that the Lebanese erythrocyte phenotypes closely resemble that of the Caucasians: nevertheless, certain novel differences are present, and possibly, there exists a phenotype that attributes to admixture of the African gene in a Middle Eastern population.