Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Emmetropisation following preterm birth.

K J Saunders1, D L McCulloch, A J Shepherd

  • 1School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK. kj.saunders@ulst.ac.uk

The British Journal of Ophthalmology
|August 20, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impaired vision in children prenatally exposed to methadone: an observational cohort study.

Eye (London, England)·2023
Same author

Tracking the Migraine Cycle Using Visual Tasks.

Vision (Basel, Switzerland)·2020
Same author

Correction: In-school eyecare in special education settings has measurable benefits for children's vision and behaviour.

PloS one·2019
Same author

In-school eyecare in special education settings has measurable benefits for children's vision and behaviour.

PloS one·2019
Same author

Parathyroid hormone-related peptide activates and modulates TRPV1 channel in human DRG neurons.

European journal of pain (London, England)·2018
Same author

Incorrect use of walking aids in patients with hip pathology.

Hip international : the journal of clinical and experimental research on hip pathology and therapy·2017

Premature birth increases the risk of abnormal refractive development, even without retinopathy of prematurity (ROP). Early refractive outcomes in preterm infants without ROP are unpredictable, with high rates of refractive errors by age 4.

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Pediatrics

Background:

  • Premature birth is linked to increased risk of abnormal refractive development, even in the absence of retinopathy of prematurity (ROP).
  • Understanding refractive development in preterm infants without ROP is crucial for early intervention and management.
  • This study investigates the relationship between clinical risk factors and refractive development in this specific population.

Purpose of the Study:

  • To examine the relationship between clinical risk factors and refractive development in preterm infants without ROP.
  • To compare refractive development between preterm and full-term infants.
  • To identify predictors of refractive outcomes at 4 years of age in preterm infants.

Main Methods:

  • Cycloplegic refraction was measured at multiple time points (birth, term, 6, 12, 48 months corrected age) in 59 preterm infants.

Related Experiment Videos

  • Perinatal history and cranial ultrasound data were collected.
  • A control group of 40 full-term infants was also studied.

    • Main Results:

    • Preterm infants without ROP exhibited higher rates of myopia and anisometropia compared to full-term infants.
    • While early emmetropization occurred, preterm infants remained more myopic at term age.
    • Infants born weighing <1500g had persistent anisometropia, and abnormal cranial ultrasounds were linked to higher hyperopia.
    • Nineteen percent of preterm infants had clinically significant refractive errors by 4 years of age.

    Conclusions:

    • Preterm infants without ROP demonstrate distinct early emmetropization patterns and high rates of refractive error.
    • Neither clinical risk factors nor early refractive error measures reliably predicted refractive outcomes at 4 years.
    • Further research is needed to understand long-term visual outcomes and potential interventions for preterm infants.