[The effect of heterologous duodenal content on the motor activity of the duodenum]

The authors carried out studies on 15 rabbits (9 controls and 6 experimental and examined the motor activity of the duodenum after infusing duodenal content from patients with clinicaly established diagnosis of chronic hepatitis at precirrhotic stage. The duodenal secretion obtained from the patients, was examined in advance and the activity of enterokinase and trypsin was determined. The obtained results showed that during infusion of saline or duodenal content, taken from healthy persons, the control group did not reveal any change in the motor activity of the duodenum. In the experimental group after infusion fo duodenal content, taken from patients with liver disease, there was a demonstrative inhibition of the motor activity of the duodenum after the third infusion in all trials. The motor activity was vot normalized for a period of 5-6 hours. There was a reduction in the activity of the enzymes enerokinase and trypsin under the normal values in the doudenal content, taken from patients with chronic hepatitis before its infusion. This coincided with the literary data.