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Updated: Sep 29, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Importance of transition zone biopsies in patients undergoing ultrasound-guided prostate systemic biopsies for the
O Ishizuka1, K Iijima, M Ishikawa
1Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan. ishizuk@hsp.md.shinshu-u.ac.jp
Introduction:
We analyze the efficacy of routine transition zone biopsies in patients undergoing ultrasound-guided systemic prostate biopsies for the first time because of a suspicious digital rectal examination or an elevated serum prostate-specific antigen (PSA) level.
Patients And Methods:
During systemic prostate biopsy two or four additional transition zone biopsies were performed in 192 consecutive patients: in 182 because of a serum PSA concentration >4.1 ng/ml and in 10 because of a suspicious digital rectal examination and a serum PSA level <4.0 ng/ml.
Results:
The overall prostate cancer detection rate was 37.5% (72/192). In 24 patients (33.3%), cancer was only detected in the peripheral zone, in 3 (4.2%) only in the transition zone, and in 45 (62.5%) in both zones.
Conclusion:
Transition zone biopsies performed at the first time of systemic prostate biopsy seem to have a low efficacy.
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