Related Experiment Video
Updated: Aug 9, 2026

An Improved Method for the Preparation of Type I Collagen From Skin
Published on: January 21, 2014
Amelioration of relapsing polychondritis in a child treated with oral collagen
M J Navarro1, G C Higgins, K M Lohr
1Department of Pediatrics, University of Tennessee, Memphis, USA.
Abstract:
Relapsing polychondritis (RP) is a disease characterized by inflammation and the destruction of cartilage. The detection of antibodies to native type II collagen (CII) in the sera of some patients with relapsing polychondritis suggests that autoimmunity to this cartilage specific protein plays a role in the pathogenesis of the disease. RP is so rare that controlled therapeutic trials have not been carried out. We describe herein a child with RP who had amelioration of symptoms and a deviation in the cellular immune response to CII after being treated with daily oral CII as a toleragen.
Related Concept Videos
Connective Tissue Cell Types
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Rheumatic Heart Disease I: Introduction

