Mechanical ventilation strategies: what's new and what's worth keeping?
Related Experiment Video
Updated: Sep 29, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
1Department of Respiratory Care, Ellison 401, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114-2696, USA. dhess@partners.org.
Abstract:
Many technologic and management strategies related to mechanical ventilation have been introduced in recent years. Strategies that avoid intubation and get patients extubated sooner decrease costs related to mechanical ventilation. In general, "people" solutions such as weaning protocols are preferable to "technology" solutions such as new ventilator modes. It must be remembered that mechanical ventilation is supportive-it is not curative-and has the potential to do harm if applied incorrectly. There is an increasing list of examples in which short-term physiologic outcomes such as improvements in blood gas values are not related to patient-important outcomes such as survival. When new mechanical ventilation technology and strategies are introduced, a question we need to ask ourselves is whether these are solutions for problems or whether these are simply solutions in search of problems.
Related Concept Videos
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
