Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preliminary clinical experience with the Bryan Cervical Disc Prosthesis.

Jan Goffin1, Adrian Casey, Pierre Kehr

  • 1Department of Neurosurgery, University Hospital Gasthuisberg, Leuven, Belgium. jan.goffin@uz.kuleuven.ac.be

Neurosurgery
|August 22, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anatomy-corrected metabolic asymmetry predicts seizure freedom after surgery in focal cortical dysplasia.

European journal of nuclear medicine and molecular imaging·2026
Same author

Intracranial electroencephalographic approaches in the intensive care unit: Safety, feasibility, and coverage.

Epilepsia·2026
Same author

Open Fetal Versus Postnatal Repair of Spina Bifida Aperta-A Comparison of Neonatal Outcomes.

Prenatal diagnosis·2026
Same author

Bridging the Frontozygomatic Gap in Fronto-Orbital Advancement Using Autologous Bone Bead Grafts, a Technical Note.

The Journal of craniofacial surgery·2025
Same author

Reply to Taal et al. Comment on "Iasella et al. Close Follow-Up of Patients with Neurofibromatosis Type 1 Reduces the Incidence of Malignant Peripheral Nerve Sheath Tumour. <i>Cancers</i> 2025, <i>17</i>, 1306".

Cancers·2025
Same author

Exploring perivascular epithelioid cell tumors (PEComas) in the CNS: insights from two case reports and a comprehensive literature review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2025

This study shows that the Bryan Cervical Disc Prosthesis effectively treats cervical disc disease, relieving symptoms and maintaining motion. Early results indicate a safe and beneficial alternative to spinal fusion.

Area of Science:

  • Orthopedics
  • Neurosurgery
  • Biomedical Engineering

Background:

  • Accelerated degeneration of adjacent disc levels is a known risk following cervical spine fusion due to increased stress.
  • Functional intervertebral disc prostheses aim to preserve motion and protect adjacent discs, offering an alternative to fusion.

Purpose of the Study:

  • To evaluate the efficacy of the Bryan Cervical Disc Prosthesis in treating single-level cervical degenerative disc disease.
  • To assess neurological symptom relief, functional improvement, pain reduction, and maintenance of motion post-implantation.

Main Methods:

  • A prospective, multicenter trial involving patients with symptomatic cervical radiculopathy/myelopathy.
  • Implantation of the Bryan Cervical Disc Prosthesis following anterior cervical discectomy.

Related Experiment Videos

  • Evaluation of pain, neurological function, and range of motion at scheduled follow-up periods.

    • Main Results:

    • Clinical success rates of 86% at 6 months and 90% at 1 year, exceeding the 85% acceptance criterion.
    • No measurable device subsidence at 1 year; minimal evidence of migration in two patients.
    • Maintained mean range of motion of 9 +/- 5 degrees in flexion-extension, with no device explantations or revisions.

    Conclusions:

    • The Bryan prosthesis alleviates neurological symptoms and signs, comparable to anterior cervical discectomy and fusion.
    • Radiographic evidence supports preserved range of motion, indicating a safe procedure with rapid recovery.
    • Long-term follow-up (≥5 years) is necessary to confirm sustained functionality and assess effects on adjacent motion segments.