Related Experiment Video

Updated: Aug 18, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Idiopathic multifocal intracardiac and pulmonary thrombosis: successful treatment with rTPA

R Holzer1, I Peart, G Ciotti

  • 1Department of Pediatric Cardiology, Royal Liverpool Children's NHS Trust, Alder Hey, Eaton Road, Liverpool, L12 2AP, United Kingdom. Holzer@doctors.org.uk

Pediatric Cardiology
|August 22, 2002
PubMed

Insights

Idiopathic intracardiac and pulmonary thrombosis in a child was successfully treated with recombinant tissue plasminogen activator (rTPA). This case highlights the importance of considering cardiopulmonary thrombosis in pediatric respiratory distress.

Area of Science:

  • Pediatric Cardiology
  • Hematology
  • Pulmonology

Background:

  • Idiopathic intracardiac and pulmonary thrombosis is a rare but serious condition in children.
  • Respiratory distress is a common presenting symptom in pediatric cardiopulmonary diseases.

Observation:

  • A 21-month-old boy presented with a one-month history of respiratory symptoms.
  • The patient was diagnosed with idiopathic multichamber intracardiac and pulmonary thrombosis.

Findings:

  • Successful treatment of pediatric intracardiac and pulmonary thrombosis was achieved using recombinant tissue plasminogen activator (rTPA).
  • Review of literature and reported cases provides insights into etiology and risk factors.

Implications:

  • Cardiopulmonary thrombosis should be considered in the differential diagnosis of respiratory distress in children.
  • rTPA is a viable therapeutic option for pediatric intracardiac and pulmonary thrombosis.

More Related Videos

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...