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05:15
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
A new approach to functionalized spiropiperidines through tandem RCM and nitrogen-directed reactions
Andrew S Edwards1, Robert A J Wybrow, Craig Johnstone
1Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, UK S3 7HF.
Chemical Communications (Cambridge, England)
|August 23, 2002
Abstract:
The synthesis of a functionalized spiropiperidine via a tandem ring closing metathesis strategy is described, furthermore, the regio- and stereoselective functionalization of this compound has been achieved through a novel nitrogen-directed epoxidation reaction.
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