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Related Experiment Videos

Female pattern hair loss.

M P Birch1, S C Lalla, A G Messenger

  • 1Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.

Clinical and Experimental Dermatology
|August 23, 2002
PubMed
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Female pattern hair loss, common in aging women, involves diffuse hair thinning on the scalp. Its causes are multifactorial, potentially involving both androgen-dependent and independent mechanisms, with limited treatment options available.

Area of Science:

  • Dermatology
  • Genetics
  • Endocrinology

Background:

  • Female pattern hair loss (FPHL) is a prevalent condition affecting scalp hair density, particularly on the crown and frontal areas.
  • Often considered the female equivalent of male androgenetic alopecia, its precise hormonal influence remains unclear.
  • The condition's prevalence escalates with age, significantly impacting patients' quality of life.

Purpose of the Study:

  • To elucidate the complex etiology of female pattern hair loss.
  • To discuss the role of androgens and other potential contributing factors.
  • To review current management strategies and their efficacy.

Main Methods:

  • Review of existing literature on female pattern hair loss.
  • Analysis of clinical presentations and diagnostic criteria.

Related Experiment Videos

  • Evaluation of treatment outcomes and patient-reported quality of life.

    • Main Results:

    • FPHL is characterized by reduced hair density, with a retained frontal hairline, increasing with age.
    • While linked to hyperandrogenism in some cases, many women with FPHL show no clinical or biochemical signs of androgen excess.
    • The condition is likely a multifactorial, genetically determined trait involving both androgen-dependent and independent pathways.

    Conclusions:

    • Female pattern hair loss is a complex condition with a multifactorial genetic basis, not solely driven by androgens.
    • Management requires awareness of severe quality-of-life impacts, which may not correlate with objective hair loss severity.
    • Current treatment options offer modest improvements in hair density for some individuals.