Overview of international collaborative group prostate cancer trials

Clinical trials in prostate cancer have gained increasing influence upon the practice of medicine. A survey was conducted of ongoing International Collaborative Group Phase III trials in localized disease, high risk and locally advanced disease, post prostatectomy, rising PSA, metastatic disease, hormone refractory prostate cancer, chemoprevention, and screening. International cooperation has the advantage of faster recruitment of patients in order to more quickly answer important scientific questions. True international collaboration can avoid duplication of efforts and promote mutual planning of trials. It is essential to treat patients with prostate cancer in the framework of clinical trials since there are still many unanswered questions.