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Double round hybridization of membrane based cDNA arrays: improved background reduction and data replication

David M Donovan1, Kevin G Becker

  • 1DNA Array Unit, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224-6825, USA.

Summary

This study introduces simple modifications to radioactive microarray experiments. These changes improve data reproducibility, allow recovery from failed experiments, and generate replicate data cost-effectively.

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