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[False hyperchloremia in a bromide intoxication].

A Laboudi1, F Vincent, M A Costa

  • 1Service de néphrologie A (Pr JD. Sraër), hôptial Tenon, 75970 Paris, France. asmaalab@hotmail.com

Annales Francaises D'Anesthesie Et De Reanimation
|August 24, 2002
PubMed
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Bromide intoxication can mimic false hyperchloremia, a condition indicated by a negative anion gap. Prompt rehydration effectively lowered bromide levels, confirming this diagnostic clue.

Area of Science:

  • Clinical Chemistry
  • Toxicology
  • Internal Medicine

Background:

  • Hyperchloremia is an electrolyte imbalance that can be caused by various factors.
  • A negative anion gap is an uncommon laboratory finding that warrants further investigation.

Observation:

  • A patient with a history of depression presented with false hyperchloremia.
  • Bromide intoxication was suspected as the underlying cause of the electrolyte disturbance.

Findings:

  • The diagnosis of bromide intoxication was confirmed by elevated serum bromide concentrations exceeding 20 mmol/L.
  • Rehydration therapy was successful in reducing the patient's bromide levels.

Implications:

  • Hyperchloremia with a negative anion gap serves as a critical diagnostic indicator for bromide intoxication.

Related Experiment Videos

  • This case highlights the importance of considering toxicological causes in patients with unexplained electrolyte abnormalities.