Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Factor XIII and wound healing].

G Wozniak1, Th Noll

  • 1Klinik für Gefässchirurgie, Knappschaftskrankenhaus Bottrop. gernold.wozniak@kk-bottrop.de

Hamostaseologie
|August 24, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-invasive methods for diagnosing pregnancy in cows and their real value.

Polish journal of veterinary sciences·2024
Same author

Ultrahypofractionated CyberKnifeTM based stereotactic radiotherapy versus conventional radiotherapy in patients with prostate cancer - acute toxicity evaluation in two phase II prospective studies.

Neoplasma·2017
Same author

Acute toxicity of robotic ultrahypofractionated radiotherapy CyberKnifeTM in prostate cancer patients.

Neoplasma·2015
Same author

Daily image-guidance in prostate cancer radiotherapy - implications for treatment margins.

Neoplasma·2015
Same author

Split-course accelerated hyperfractionated irradiation (CHA-CHA) as a sole treatment for advanced head and neck cancer patients-final results of a randomized clinical trial.

The British journal of radiology·2014
Same author

Optimization of circulating cell-free DNA recovery for KRAS mutation and HPV detection in plasma.

Cancer biomarkers : section A of Disease markers·2014

Diabetic wounds and calf ulcers often involve increased vascular permeability, hindering healing. Plasma transglutaminase (factor XIIIa) shows promise as a therapeutic strategy to control this permeability and improve wound healing outcomes.

Area of Science:

  • Biomedical science
  • Vascular biology
  • Wound healing research

Context:

  • Chronic wounds like diabetic ulcers and calf ulcerations exhibit impaired endothelial barrier function and increased vascular permeability.
  • This increased permeability is a significant pathophysiological factor in non-healing wounds.
  • Existing treatments often struggle to address the underlying vascular issues in these chronic wounds.

Purpose:

  • To investigate the role of plasma transglutaminase (factor XIIIa) in regulating vascular permeability.
  • To explore factor XIIIa as a potential therapeutic target for improving wound healing in conditions characterized by increased vascular permeability.

Summary:

  • Clinical and experimental studies suggest that plasma transglutaminase (factor XIIIa) can modulate vascular permeability.

Related Experiment Videos

  • Targeting factor XIIIa may offer a novel approach to manage the increased permeability associated with chronic wound conditions.
  • Controlling vascular permeability is therapeutically relevant for enhancing wound repair.

    • Impact:

    • Identifies factor XIIIa as a potential therapeutic agent for chronic wound management.
    • Provides a basis for developing new treatments focused on vascular barrier function.
    • Offers a novel strategy to improve healing outcomes for patients with diabetic wounds and venous leg ulcers.