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[Ischemic colitis induced by cocaine. Clinical case].

Camilo Boza1, Bruno Dagnino, Ana María Garrido

  • 1Departamento de Cirugía Digestiva, Facultad de Medicina, Pontificia Universidad Católica de Chile. camiloboza@hotmail.com

Revista Medica De Chile
|August 27, 2002
PubMed
Summary

A young man with a history of substance abuse developed acute peritonitis due to multiple cecal perforations. Surgery revealed ischemic colitis, a rare condition linked to cocaine use.

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Area of Science:

  • Gastroenterology
  • Toxicology
  • Surgery

Background:

  • Cocaine abuse is associated with various systemic complications.
  • Gastrointestinal complications of cocaine abuse are infrequently reported.
  • Ischemic colitis is a condition characterized by reduced blood flow to the colon.

Observation:

  • A 29-year-old male with a history of cocaine abuse and excessive alcohol intake presented with acute peritonitis.
  • Surgical exploration revealed multiple perforations of the cecum.
  • Pathological examination of the resected bowel segment confirmed ischemic colitis.

Findings:

  • The case highlights a rare presentation of ischemic colitis secondary to cocaine abuse.
  • A literature review identified 22 previously reported cases of cocaine-associated ischemic colitis.

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  • This suggests a potential, albeit uncommon, link between stimulant drug use and bowel ischemia.

    • Implications:

    • Clinicians should consider cocaine abuse in the differential diagnosis of young patients presenting with acute abdominal conditions, particularly bowel ischemia.
    • Early recognition and cessation of cocaine use may be crucial in managing such cases.
    • Further research is warranted to elucidate the precise mechanisms underlying cocaine-induced ischemic colitis.