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Ageing: repair and transcription keep us from premature ageing
1Genome Damage and Stability Centre, University of Sussex, Falmer, BN1 9RQ, Brighton, UK. arlehmann@sussex.ac.uk
Current Biology : CB
|August 27, 2002
Abstract:
Trichothiodystrophy (TTD) is a complex disorder caused by mutations in the XPD gene which affect both DNA repair and transcription. A mouse with a TTD mutation has now been found to display remarkable signs of premature ageing.