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Published on: June 11, 2011
Prevalence of intestinal parasitic pathogens in HIV-seropositive individuals in Northern India
Mohandas1, Rakesh Sehgal, Archana Sud
1Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Abstract:
To assess the prevalence of intestinal parasitic infections in human immunodeficiency virus (HIV)-seropositive subjects, fecal samples were collected from 120 HIV-seropositive patients and were analyzed for various intestinal parasites. Thirty-six patients (30%) were found to harbor an intestinal parasite. Cryptosporidium parvum was the most common (10.8%), followed by Giardia lamblia (8.3%). Cyclospora cayetanensis and Blastocystis hominis each were detected in 3.3% of the patients, while Isospora belli and Enterocytozoon bieneusi were each detected in 2.5% of the patients. The other parasites observed were Entamoeba histolytica/E. dispar in two cases and hookworm ova in one patient. Of the 36 patients who tested positive for intestinal parasites, 27 (75%) had diarrhea. The most common parasite, which was associated with diarrhea, was C. parvum. The present study highlights the importance of testing for intestinal parasites in patients who are HIV-positive, and emphasizes the necessity of increasing awareness among clinicians regarding the occurrence of these parasites in this population.
Insights
Intestinal parasitic infections affect 30% of human immunodeficiency virus (HIV)-positive patients, with Cryptosporidium parvum being most common. Early detection and awareness are crucial for managing these infections in immunocompromised individuals.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Immunocompromised Hosts
Background:
- Human immunodeficiency virus (HIV) infection can compromise the immune system, increasing susceptibility to opportunistic infections.
- Intestinal parasitic infections are a significant cause of morbidity in immunocompromised individuals, particularly those with HIV.
Purpose of the Study:
- To determine the prevalence of intestinal parasitic infections in HIV-seropositive individuals.
- To identify the specific types of intestinal parasites and their association with clinical symptoms like diarrhea.
Main Methods:
- Fecal samples were collected from 120 HIV-seropositive patients.
- Samples were analyzed to detect various intestinal parasites using appropriate diagnostic methods.
Main Results:
- 30% of HIV-seropositive patients (36 out of 120) were infected with at least one intestinal parasite.
- Cryptosporidium parvum (10.8%) and Giardia lamblia (8.3%) were the most prevalent parasites.
- 75% of infected patients experienced diarrhea, with C. parvum being the most frequently associated parasite.
Conclusions:
- Intestinal parasitic infections are common in HIV-seropositive patients.
- Routine screening for intestinal parasites is recommended in this population.
- Increased clinician awareness is necessary for timely diagnosis and management.
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