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Relationship between urinary symptoms and disease-related parameters in multiple sclerosis
1Department of Urology, Yamanashi Medical University, 1110 Shimokato, Tamaho, Yamanashi 409-3898, Japan. iaraki@res.yamanashi-med.ac.jp
Journal of Neurology
|August 27, 2002
Summary
Over half of multiple sclerosis patients experience voiding dysfunction, with irritative urinary symptoms correlating with disease severity. These symptoms can aid in neurological diagnosis.
Area of Science:
- Neurology
- Urology
Background:
- Multiple sclerosis (MS) is a chronic demyelinating disease affecting the central nervous system.
- Voiding dysfunction is a common but often underreported complication in MS patients.
- Understanding the prevalence and correlates of voiding dysfunction is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of voiding dysfunction in patients with multiple sclerosis (MS).
- To investigate the association between voiding dysfunction and MS disease parameters, including severity, duration, lesion site, age, and sex.
Main Methods:
- Quantitative evaluation of lower urinary tract symptoms using the International Prostate Symptom Score in MS patients.
- Assessment of lesion site in the central nervous system via neurological examination and magnetic resonance imaging.
Main Results:
- Symptomatic voiding dysfunction was identified in 53% of MS patients.
- Irritative urinary symptoms correlated significantly with MS disease severity and duration.
- Spinal cord lesions were associated with the degree of urinary symptoms; age and sex showed no significant influence.
Conclusions:
- Urinary symptoms, particularly irritative ones, serve as indicators of MS disease status.
- Quantified urinary symptom assessment can potentially assist in the neurological diagnosis and management of MS.
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