Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Measurable differences between sequential and parallel diagnostic decision processes for determining stroke subtype:

Cathy M Helgason1, Fred A Watkins, Thomas H Jobe

  • 1Department of Neurology, University of Illinois College of Medicine, Chicago, Illinois, USA. helgason@uic.edu

Thrombosis and Haemostasis
|August 28, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>'An experience of meaning'</i>: A 20-year prospective analysis of delusional realities in schizophrenia and affective psychoses.

Frontiers in psychiatry·2022
Same author

'Are these my thoughts?': A 20-year prospective study of thought insertion, thought withdrawal, thought broadcasting, and their relationship to auditory verbal hallucinations.

Schizophrenia research·2022
Same author

A word is worth a thousand pictures: A 20-year comparative analysis of aberrant abstraction in schizophrenia, affective psychosis, and non-psychotic depression.

Schizophrenia research·2021
Same author

Long-term effectiveness of antipsychotics.

Psychological medicine·2021
Same author

Twenty-year effects of antipsychotics in schizophrenia and affective psychotic disorders.

Psychological medicine·2021
Same author

Clarifying the direction of impact of negative symptoms and neurocognition on prospective work functioning in psychosis: A 20-year longitudinal study.

Schizophrenia research·2020

This study compares two ways to diagnose stroke subtypes. One method uses a sequence of tests based on how often each subtype occurs. The other allows multiple tests to be done at the same time. The researchers found that the first method tends to miss some cases of stroke severity. The second method better captures multiple interacting health issues. The study used severity scores to compare the results. The authors suggest that allowing multiple diagnoses could improve stroke diagnosis accuracy.

Area of Science:

  • Neurological diagnostic methodologies
  • Stroke subtype classification
  • Medical decision-making processes

Background:

Stroke diagnosis relies on identifying causal subtypes. Current methods follow a sequence of tests based on subtype frequency. This approach assigns diagnosis once a single test is positive. However, some patients may have multiple pathologies simultaneously. Prior research has shown that stroke subtypes differ in their underlying mechanisms. It was already known that ischemic stroke involves multiple interacting factors. No prior work had resolved how to account for these interactions in diagnosis. This gap motivated the exploration of parallel diagnostic methods. That uncertainty drove the development of new numeric criteria for comparison.

Purpose Of The Study:

This study aimed to compare two diagnostic procedures for stroke subtypes. One method uses sequential testing based on subtype frequency. The other allows for parallel testing of multiple hypotheses. The goal was to assess how these methods affect diagnosis outcomes. The researchers propose that parallel testing might better capture interacting pathologies. They tested both methods on thirty patients with ischemic stroke. The study sought to quantify differences in diagnostic results. The authors suggest this could improve diagnostic accuracy.

Keywords:
stroke diagnosisparallel testingischemic strokediagnostic algorithms

Frequently Asked Questions

Sequential testing assigns diagnosis after one positive result, while parallel testing evaluates multiple hypotheses simultaneously.

They used severity assessments as ordered sets of three numbers between 0 and 1 for each patient.

The researchers propose it captures multiple interacting pathologies that sequential testing ignores.

They represent the diagnostic outcome for each patient under both methods.

Related Experiment Videos

Main Methods:

The researchers applied two diagnostic approaches to thirty patients with ischemic stroke. One method used sequential testing based on subtype frequency. The other tested multiple hypotheses simultaneously. For each patient, both methods produced a severity assessment. This assessment was an ordered set of three numbers between 0 and 1. The study compared the results from both diagnostic procedures. The authors used novel numeric criteria to evaluate differences. The methods focused on thrombosis-related ischemic stroke.

Main Results:

The computations revealed consistent differences between the two methods. The sequential approach tended to under-diagnose stroke severity. It also failed to account for interactions between pathologies. The parallel method captured multiple simultaneous pathologies. The severity scores from both methods showed measurable variation. The ordered sets of numbers highlighted these differences clearly. The sequential method produced simpler but less comprehensive results. The parallel method provided a more detailed diagnostic picture.

Conclusions:

The authors propose that sequential testing may miss complex interactions. They suggest parallel testing better reflects real-world pathologies. The study shows measurable differences in diagnostic outcomes. The sequential method underestimates stroke severity in some cases. The parallel method accounts for multiple interacting factors. These findings imply limitations in current diagnostic practices. The authors claim that parallel testing could improve stroke diagnosis. They emphasize the need for further validation of this approach.

It means the method may miss stroke severity due to its inability to account for multiple pathologies.

They propose that parallel testing could improve stroke diagnosis by better reflecting interacting pathologies.