Successful tolerance induction to spiramycin in pregnancy

Eleonora Nucera1, Chiara Roncallo, Lucia Masini

  • 1Department of Allergology, Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, Rome, Italy.

We report the cases of 2 pregnant patients, suffering from toxoplasmosis, who developed an erythematous, maculopapular rash during spiramycin therapy that disappeared with discontinuation of the drug. The 2 patients underwent a tolerance induction protocol with spiramycin and were able to continue therapy with this drug until the end of their pregnancies, with no side-effects.