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Recent trends in hospitalization for diabetic ketoacidosis in ontario children
Jacqueline R Curtis1, Teresa To, Sarah Muirhead
1Department of Pediatrics, Division of Endocrinology, the Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Insights
Diabetic ketoacidosis (DKA) hospitalizations in children remained stable despite reduced non-DKA admissions, indicating a need for targeted prevention strategies. Geographic variations in DKA rates persist, highlighting areas for intervention.
Area of Science:
- Pediatric Endocrinology
- Public Health
- Health Services Research
Background:
- Ambulatory care improvements have reduced non-DKA hospitalizations in children with diabetes.
- Diabetic ketoacidosis (DKA) remains a significant concern in pediatric diabetes management.
Purpose of the Study:
- To analyze trends and geographic disparities in pediatric diabetic ketoacidosis (DKA) hospitalization rates in Ontario between 1991 and 1999.
- To assess the impact of healthcare interventions on DKA admissions.
Main Methods:
- Utilized Canadian Institute for Health Information (CIHI) data for 15,872 diabetes-related hospital admissions in children under 19.
- Conducted small area variation analysis comparing high and low DKA admission rates.
- Analyzed trends in DKA vs. non-DKA admissions, length of stay, and fatality rates.
Main Results:
- Overall diabetes admissions decreased by 19%; non-DKA admissions fell by 29%, while DKA admissions remained stable.
- Average length of hospital stay decreased for both DKA and non-DKA admissions.
- Geographic variation in DKA admissions was stable, with a 3.7-fold difference between regions.
Conclusions:
- While non-DKA admissions have decreased due to ambulatory care, DKA rates in children with diabetes remain a concern.
- A 3.7-fold geographic disparity in DKA admissions is clinically significant, necessitating targeted prevention.
- Further prevention strategies are crucial, especially in regions with higher DKA hospitalization rates.
Objective:
To investigate trends and geographic variation in diabetic ketoacidosis (DKA) hospitalization rates among children in Ontario from 1991 to 1999.
Research Design And Methods:
Canadian Institute for Health Information (CIHI) data were used to identify 15,872 diabetes-related hospital admissions in children younger than 19 years in Ontario from 1991 to 1999. Of these, 5,008 admissions were because of DKA and 10,864 admissions were because of conditions other than DKA (non-DKA). Small area variation analysis was used to compare areas with high versus low DKA admission rates.
Results:
There was a 19% relative decrease in the overall diabetes admission rate over the study period. Non-DKA admissions decreased by 29%, whereas DKA admissions remained stable. Total days of care decreased by 393 days per year for non-DKA admissions and by 99 days per year for DKA admissions. The average length of hospital stay decreased from 4.9 to 3.5 days for non-DKA admissions and from 4.5 to 3.2 days for DKA admissions. The fatality rate was 0.19% for non-DKA admissions and 0.18% for DKA admissions. Variation across geographic areas remained stable for DKA over the study period (Kendall's correlation coefficient 0.64, P = 0.017) with an average 3.7-fold difference between the lowest and highest regions.
Conclusions:
Increased ambulatory care efforts for children with type 1 diabetes in Ontario have successfully reduced non-DKA admission rates. However, DKA admission rates have remained stable. Geographic variation for DKA admissions is low, but the observed 3.7-fold difference is clinically important for a preventable complication with a significant potential for long-term morbidity and mortality. Prevention strategies are needed, particularly in areas identified with the highest rates.
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