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[ULCERATIVE COLITIS: A 52 YEARS RETROSPECTIVE STUDY]

Luis Illescas, Luis García, Frida Faggioni

    Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
    |August 28, 2002
    PubMed
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    This study on chronic ulcerative colitis in Peru found it is rare, primarily affecting adults aged 30-40. Most patients experienced moderate symptoms, with low mortality and no link to colon cancer.

    Area of Science:

    • Gastroenterology
    • Internal Medicine
    • Epidemiology

    Background:

    • Chronic ulcerative colitis (CUC) is an inflammatory bowel disease with varying global incidence.
    • Understanding CUC demographics and clinical presentation in specific regions like Peru is crucial for healthcare planning.

    Purpose of the Study:

    • To describe the epidemiological and clinical characteristics of chronic ulcerative colitis in a Peruvian cohort.
    • To assess disease severity, endoscopic findings, and mortality rates associated with CUC in Peru.

    Main Methods:

    • Retrospective analysis of 74 patients diagnosed with chronic ulcerative colitis.
    • Data collection included patient demographics, symptoms, disease severity, endoscopic findings, and outcomes.

    Main Results:

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    • The highest incidence of CUC was observed in patients aged 30-40 years.
    • Most frequent symptoms included diarrhea (95%), rectal bleeding (87%), and abdominal pain (79%).
    • Moderate symptom severity was most common (46.6%), with significant endoscopic findings like friability (93.2%) and hyperemia (90.5%). Mortality rate was 6.7%.

    Conclusions:

    • Chronic ulcerative colitis appears to be rare in Peru.
    • The disease predominantly presents with moderate symptoms and has a low associated mortality.
    • No association between CUC and colon cancer was evidenced in this study cohort.