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Lung-stage protein profile and antigenic relationship between Ascaris lumbricoides and Ascaris suum
Abebe Wossene1, Naotoshi Tsuji, Harue Kasuga-Aoki
1Laboratory of Parasitic Diseases, National Institute of Animal Health, National Agricultural Research Organization, Tsukuba, Ibaraki 305-0856, Japan.
The Journal of Parasitology
|August 29, 2002
Abstract:
The protein profile and antigenic properties of lung-stage larvae of Ascaris lumbricoides and A. suum were studied using 2-dimensional electrophoresis and immunoblot analysis, respectively. The protein profiles of the 2 parasites were identical except for the presence of only 1 major protein spot specific for each. There was a complete cross-reactivity between the 2 parasites at the immunological level, and no specific antigen was recognized using specific antibody raised against the 2 parasites in rabbits.