Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[In vitro study of transcutaneous inorganic mercury absorption from solid soil].

P Sartorelli1, L Montomoli, A G Sisinni

  • 1Instituto di Medicina del Lavoro, Università degli Studi di Siena.

La Medicina Del Lavoro
|August 29, 2002
PubMed
Summary

Skin absorption of mercury chloride (HgCl2) is lower when applied in soil. In vitro studies show mercury concentrations in receiving fluid were below detection limits when using soil as a vehicle, indicating low dermal risk from contaminated soil.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Solutions and Challenges in Focusing Trap and Spectral Deconvolution for Characterization of Odor Active VOCs in Hot Mix-Asphalt.

Journal of mass spectrometry : JMS·2026
Same author

Unveiling the spectrum of sudden cardiac death: a multidisciplinary analysis from the Friuli Venezia Giulia registry.

Frontiers in cardiovascular medicine·2025
Same author

Preventive oral kefir supplementation protects mice from ovariectomy-induced exacerbated allergic airway inflammation.

Beneficial microbes·2021
Same author

Extranodal extension in head and neck squamous cell cancer: is there a role for further stratification?

The British journal of oral & maxillofacial surgery·2021
Same author

Personal solar ultraviolet radiation dosimetry in an occupational setting across Europe.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

Polycyclic Aromatic Hydrocarbons Exposure Assessment in a Refractory Brick Production.

Annals of work exposures and health·2019

Area of Science:

  • Environmental Science
  • Toxicology
  • Dermatology

Context:

  • Mercury compounds are readily absorbed through the skin, necessitating occupational exposure limits.
  • Industrial activities and mining have historically led to significant mercury contamination in soil.
  • Understanding dermal uptake requires considering factors beyond the pure substance, such as soil binding.

Purpose:

  • To investigate the percutaneous penetration of mercury chloride (HgCl2) using an in vitro diffusion cell system with human skin.
  • To evaluate mercury absorption from soil as a potential exposure route.
  • To determine the influence of different mercury chloride concentrations and vehicles (buffered solution vs. soil) on dermal uptake.

Summary:

  • An in vitro diffusion cell system with human cadaver skin was used to study mercury chloride penetration.

Related Experiment Videos

  • Mercury chloride was applied at varying concentrations using both buffered solutions and soil as vehicles.
  • Absorption rates were lower at higher HgCl2 concentrations, and mercury levels in the receiving fluid were undetectable when soil was the vehicle.

    • Impact:

    • Findings suggest that skin contamination with inorganic mercury in soil may not pose a significant dermal risk.
    • This research aids in establishing safe daily exposure levels for mercury in soil.
    • Provides crucial in vitro data for assessing dermal exposure to soil-bound contaminants.