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Updated: Aug 12, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
[Hygienic assessment of components of smoking fume]
Abstract:
Analyzing the chemical composition of smoking fume has indicated that maximum allowable concentrations (MACs) have been established for 50 of 400 well-known compounds, working area MACs were standardized for 42 of the 50 compounds, the maximum single and daily average concentrations were standardized for 34 and 30 compounds, respectively. All standards were established for 25 compounds. Despite the fact that there a large list of MACs, it is difficult to calculate the objective hygienic risk of smoking smoke since 32 compounds are contained in traces. Hygienic assessment of fume discharges from the smoking chamber by taking into account their mass and MACs demonstrated that phenols, carbonyl compounds, acids, and benz(a)pyrene which should be used to work out the unified hygienic standard are of the greatest importance.
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