Related Experiment Video
Updated: Sep 29, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Influence of number of pregnancies and total breast-feeding time on bone mineral density
Sebastián Carranza-Lira1, Jaime Paz Mera
1Gynecologic Endocrinology Service, Hospital de Gineco Obstetricia Luis Castelazo Ayala, Instituto Mexicano del Seguro Social, México DF.
Objective:
To analyze how the number of pregnancies and total breast-feeding time influence bone mineral density.
Methods:
50 healthy women aged 35 to 40 years were studied. Weight, height, number of term pregnancies, time since last pregnancy and breast-feeding time were analyzed. They were divided in three groups as follows: I: nulligravidas; II: with term pregnancies, but no breast-feeding; III: with term pregnancies, with breast-feeding. Bone absorptiometry was done on all, at lumbar column and femur. The WHO criteria were used to define osteopenia and osteoporosis. Comparison among the groups was done with Student's t-test for independent samples, and simple regression analysis was done for number of gestations, total breast-feeding time, time since last birth, and T-score at lumbar column and femur.
Results:
The women were divided as follows: 15 in group I, 15 in group II, and 20 in group III. The average age was 37.7 +/- 1.5 years. No differences were found among the three groups in analyzed variables, when comparing bone mineral density, T- and Z-scores in L1-L4 average, femoral neck, trochanter, and Ward's triangle. There was no correlation among the number of gestations, total breast-feeding time, time since last birth, or T-scores at lumbar column and femur.
Conclusion:
The number of pregnancies and breast-feeding time do not affect bone mineral density.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Remodeling
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Development of Human Microbiota