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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
Cancer by county: new resource for etiologic clues
Science (New York, N.Y.)
|September 29, 1975
Summary
Cancer mortality maps reveal geographic patterns linked to causes. Bladder cancer in males may stem from industrial exposures, while stomach cancer clusters suggest ethnic factors.
Area of Science:
- Epidemiology
- Environmental Health
- Cancer Research
Background:
- Geographic variations in cancer mortality can indicate underlying environmental or genetic risk factors.
- Understanding these patterns is crucial for targeted public health interventions and etiological research.
Purpose of the Study:
- To analyze U.S. county-level cancer mortality data to identify significant geographic patterns.
- To investigate potential industrial and ethnic determinants associated with observed cancer mortality clusters.
Main Methods:
- Utilized county-level cancer mortality data for the United States.
- Performed spatial analysis to identify geographic clusters of high cancer rates.
- Correlated identified patterns with known industrial activities and demographic/ethnic data.
Main Results:
- Identified distinct geographic patterns in cancer mortality across U.S. counties.
- Bladder cancer mortality in males showed correlations with chemical, automobile, and machinery manufacturing areas.
- Stomach cancer mortality clusters in both sexes were consistent with patterns of ethnic susceptibility.
Conclusions:
- Cancer mortality mapping highlights significant geographic disparities with potential etiological links.
- Industrial exposures, particularly in manufacturing sectors, are potential determinants for male bladder cancer.
- Ethnic background may play a role in the geographic distribution of stomach cancer.
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