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Related Experiment Videos

Isopropyl alcohol intoxication: a diagnostic challenge.

Fahim Zaman1, Aslam Pervez, Kenneth Abreo

  • 1Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. fzaman@lsuhsc.edu

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|August 30, 2002
PubMed
Summary

Isopropyl alcohol (IPA) ingestion can be fatal if not recognized and treated. This case highlights repeated IPA intoxication and reviews diagnostic and therapeutic strategies for this uncommon poisoning.

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Area of Science:

  • Toxicology
  • Internal Medicine
  • Emergency Medicine

Background:

  • Isopropyl alcohol (IPA) is a common household chemical found in rubbing alcohol and sanitizers.
  • Ingestion of IPA can lead to severe toxicity and potentially fatal outcomes if misdiagnosed or untreated.
  • Published literature on IPA intoxication is limited, underscoring the need for increased awareness.

Observation:

  • A case of recurrent isopropyl alcohol intoxication in a single patient is presented.
  • The patient's repeated ingestion highlights a potential pattern of substance misuse or self-harm.
  • Clinical presentation and laboratory findings associated with IPA toxicity were observed.

Findings:

  • Isopropyl alcohol intoxication presents diagnostic challenges due to its varied symptoms and potential for misdiagnosis.

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  • Effective management requires prompt recognition, supportive care, and consideration of specific interventions.
  • Literature review reveals a paucity of detailed case reports and treatment guidelines for IPA poisoning.

    • Implications:

    • Increased clinical suspicion for IPA intoxication is warranted in patients with altered mental status and unexplained metabolic acidosis.
    • Understanding diagnostic pitfalls is crucial for timely and accurate diagnosis of IPA poisoning.
    • This case and review emphasize the importance of recognizing and managing IPA toxicity to prevent severe morbidity and mortality.