Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sentinel node role in breast cancer surgery.

M Lazzaro1, S Giri, M Lippolis

  • 1Istituto di II Clinica Chirurgica, University La Sapienza, Rome, Italy.

European Review for Medical and Pharmacological Sciences
|August 31, 2002
PubMed
Summary

Routine axillary dissection in breast cancer surgery may be unnecessary, increasing risks without confirmed metastases. The sentinel node technique allows real-time lymph node assessment during surgery, guiding treatment decisions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pollinators support the nutrition and income of vulnerable communities.

Nature·2026
Same author

First Results on the Search for Lepton Number Violating Neutrinoless Double-β Decay with the LEGEND-200 Experiment.

Physical review letters·2026
Same author

Enhanced photodetectivity and responsivity in In<sub>10</sub>Se<sub>70</sub>Te<sub>15</sub>Bi<sub>5</sub> film by time-dependent laser irradiation for photodetector applications.

RSC advances·2025
Same author

Differentiation-Dependent Proximity Proteomics Identifies Novel Host Factors Linked to HPV16 E2 Function.

bioRxiv : the preprint server for biology·2025
Same author

Unilateral adrenal hemorrhage with variable adrenocortical dysfunction.

QJM : monthly journal of the Association of Physicians·2024
Same author

Comparative outcome of single versus two double-pigtail stents for endoscopic drainage of pancreatic fluid collections with minimal necrosis: a retrospective analysis.

Acta gastro-enterologica Belgica·2024

Area of Science:

  • Oncology
  • Surgical Oncology
  • Pathology

Background:

  • Radical breast cancer surgery traditionally involves axillary lymph node dissection.
  • Routine axillary dissection increases patient morbidity, especially when axillary metastases are absent.
  • Accurate axillary lymph node status is crucial for treatment planning but historically required complete dissection.

Purpose of the Study:

  • To evaluate the utility of the sentinel node technique in breast cancer surgery.
  • To determine if sentinel node biopsy can accurately assess axillary lymph node status.
  • To guide decisions regarding the extent of axillary lymphadenectomy.

Main Methods:

  • The study introduces the sentinel node technique for intraoperative lymph node evaluation.

Related Experiment Videos

  • This method allows for the assessment of lymph node pathology during surgery.
  • Surgeons can use this information to decide whether to proceed with full lymphadenectomy.

    • Main Results:

    • The sentinel node technique provides intraoperative information on lymph node status.
    • This enables surgeons to make informed decisions about lymphadenectomy in the operating theatre.
    • It offers a potential alternative to routine axillary dissection.

    Conclusions:

    • The sentinel node technique is a valuable tool for assessing axillary lymph node involvement in breast cancer.
    • It allows for personalized surgical management, potentially reducing unnecessary morbidity.
    • This method supports a more targeted approach to breast cancer treatment.