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Updated: Sep 29, 2026

Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles (PPAs) and Related Biomaterials
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Amino acid bromides: their N-protection and use in the synthesis of peptides with extremely difficult sequences

Alma DalPozzo1, Minghong Ni, Laura Muzi

  • 1G. Ronzoni Institute for Chemical and Biochemical Research, via G. Colombo 81, 20133 Milano, Italy.

The Journal of Organic Chemistry
|August 31, 2002
PubMed

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Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
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