Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asymmetrical membranes and surface tension.

Mounir Traïkia1, Dror E Warschawski, Olivier Lambert

  • 1Institut de Biologie Physico-Chimique, Unité Mixte de Recherche Centre National de la Recherche Scientifique 7099, Paris 75005 France.

Biophysical Journal
|August 31, 2002
PubMed
Summary

Phosphatidic acid

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stage-specific metabolic responses in blue mussels to marine shipping-related acoustic and chemical stressors.

Marine pollution bulletin·2026
Same author

Wall Teichoic Acids Are Direct Molecular Targets of Antimicrobial Peptides in Gram-Positive Bacteria.

Journal of the American Chemical Society·2026
Same author

A membrane perspective on peptide-membrane interactions: recent results from solid-state NMR.

Biomedical journal·2025
Same author

Genetic and genomic variability of <i>Spiroplasma</i> and <i>Midichloria</i> endosymbionts associated with the tick <i>Ixodes frontalis</i>.

ISME communications·2025
Same author

Reconstitution of RND tripartite multidrug complexes for single-particle electron microscopy.

Methods in enzymology·2025
Same author

Nonliving respiration: Another breath in the soil?

Science advances·2025

Area of Science:

  • Biochemistry
  • Biophysics
  • Membrane Biology

Background:

  • Phosphatidic acid's (31)P-NMR chemical shift reflects lipid packing.
  • Membrane lateral compression influences protein conformation.

Purpose of the Study:

  • To investigate lateral compression in asymmetrical lipid vesicles.
  • To understand how lipid asymmetry affects membrane properties.

Main Methods:

  • High-resolution (31)P-nuclear magnetic resonance spectroscopy.
  • Utilizing sonicated and large unilamellar vesicles with varying lipid compositions.

Main Results:

  • Monooleoylphosphatidylcholine addition caused external monolayer compression and internal monolayer dilation in sonicated vesicles.
  • In large unilamellar vesicles, both monolayers experienced increased lateral pressure.
  • Differences in vesicle type (sonicated vs. large unilamellar) led to distinct packing responses.

Conclusions:

  • Lipid asymmetry induces lateral strain, potentially modulating membrane protein conformation.
  • Vesicle curvature influences the response to lipid asymmetry.
  • Differential packing in lipid bilayers is a key factor in membrane mechanics.

Related Experiment Videos