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Triplet placentas: reference values for weights.

Halit Pinar1, Merielle Stephens, Don B Singer

  • 1Department of Pathology and Laboratory Medicine, Division of Perinatal and Pediatric Pathology, Women and Infants Hospital and Brown Medical School, 101 Dudley Street, Providence, RI 02905, USA. hpinar@wihri.org

Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
|August 31, 2002
PubMed
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Triplet placenta weights were studied, revealing they do not increase proportionally with the number of fetuses. Mean triplet placental weights are less than triple those of singleton placentas at similar gestational ages.

Area of Science:

  • Obstetrics and Gynecology
  • Pathology
  • Perinatology

Background:

  • Multiple births, including triplets, have significantly increased in industrialized nations since 1970.
  • A rise in triplet placentas submitted for pathological examination necessitates established reference values.
  • No published reference values for triplet placental weights currently exist.

Purpose of the Study:

  • To establish reference values for normal triplet placental weights across various gestational ages.
  • To compare triplet placental weight gain with that of twin placentas.
  • To analyze the relationship between placental weight and the number of fetuses in multiple gestations.

Main Methods:

  • Examination of 196 normal triplet placentas.
  • Exclusion of specimens with conditions known to affect placental weight.

Related Experiment Videos

  • Data collection and analysis of placental weights correlated with gestational age (20-38 weeks).

    • Main Results:

    • Mean triplet placental weights were determined for each gestational age from 20 to 38 weeks.
    • Triplet placental weight gain parallels that observed in twin placentas.
    • Mean triplet placental weights are less than triple the mean weights of singleton placentas at equivalent gestational ages.

    Conclusions:

    • The study provides the first reference values for normal triplet placental weights.
    • Placental weight in multiple gestations does not increase proportionately with the number of fetuses.
    • These findings are crucial for accurate pathological assessment of triplet placentas.