Related Experiment Videos
Different striatal dopamine D2 receptor occupancy in alcohol dependent patients with or without physical withdrawal
1Department of Psychiatry and Psychotherapy, University of Freiburg, Federal Republic of Germany.
Journal of Neural Transmission (Vienna, Austria : 1996)
|August 31, 2002
Abstract:
Ten male patients with type I alcohol dependency fulfilling DSM-IV criteria for alcohol dependency were investigated twice using IBZM-SPECT after alcohol withdrawal (day 2 and day 28 after withdrawal). Five patients had a history of physical withdrawal symptoms, 5 patients had no such history. The group with physical withdrawal symptoms showed higher IBZM binding in both scans indicating differences of dopaminergic neurotransmission in different subtypes of alcohol dependency.