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Updated: Sep 29, 2026

Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors
Published on: April 13, 2019
A comparative analysis of mono- and disaccharide benzyl fucopyranosides
Marco Brito-Arias1, Enrique Durán-Páramo, Ignasi Mata
1Unidad Interdisciplinaria de Biotecnología IPN, Av Acueducto s/n Col. Barrio la Laguna Ticomán, CP 07340, México DF, Mexico.
Abstract:
The syntheses and X-ray analyses of two fucopyranosides, the monosaccharide benzyl 3,4-di-O-acetyl-2-hydroxy-beta-D-fucopyranoside, C(17)H(22)O(7), and the disaccharide 1-benzyl O-(2,3-di-O-acetyl-4,6-O-benzylidene-beta-D-glucopyranosyl)-(1-->2)-3,4-O-isopropylidene-beta-D-fucopyranoside, C(33)H(40)O(12), are described. The different substituents induce small conformational changes on the fucopyranoside ring. However, the conformation of the benzyl group varies from (+)gauche for the monosaccharide to synperiplanar for the disaccharide.
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