Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Controlled versus assisted mechanical ventilation.

Christian Putensen1, Rudolf Hering, Hermann Wrigge

  • 1Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany. putensen@uni-bonn.de

Current Opinion in Critical Care
|September 3, 2002
PubMed
Summary

Maintaining spontaneous breathing during mechanical ventilation benefits patients with severe lung issues, leading to faster recovery and shorter ICU stays. This approach is recommended unless contraindications exist.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Updated consensus terminology and definitions in chest electrical impedance tomography.

Physiological measurement·2026
Same author

Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial.

Intensive care medicine·2026
Same author

Phosphorylated toll-like receptor 4 defines a high-risk sepsis endotype.

Critical care (London, England)·2026
Same author

Effects of Intraoperative Prone Versus Supine Positioning on Postoperative Delirium.

Geriatrics (Basel, Switzerland)·2026
Same author

Diagnostic performance of β-(1→3)-D-glucan, two <i>Candida</i> antigen, and five anti-<i>Candida</i> antibody assays in ICU patients with sepsis and high risk for invasive candidiasis: a secondary endpoint of the CandiSep randomized clinical trial.

Journal of clinical microbiology·2026
Same author

Human Cytomegalovirus Serostatus Defines Cytokine-Based Predictive Signatures in Sepsis.

Pathogens (Basel, Switzerland)·2026

Area of Science:

  • Critical Care Medicine
  • Pulmonary Medicine
  • Mechanical Ventilation

Background:

  • Mechanical ventilation is a critical support for patients with severe pulmonary dysfunction.
  • Traditionally, controlled mechanical ventilation followed by weaning was the standard approach.
  • The role of spontaneous breathing during mechanical ventilation requires further investigation.

Purpose of the Study:

  • To evaluate the benefits of maintaining spontaneous breathing during mechanical ventilation in patients with severe pulmonary dysfunction.
  • To determine if spontaneous breathing can be a primary ventilatory support modality.
  • To compare outcomes between maintained spontaneous breathing and traditional ventilation strategies.

Main Methods:

  • Review of currently available data on spontaneous breathing during mechanical ventilation.

Related Experiment Videos

  • Analysis of clinical outcomes, including days on ventilation, extubation time, and ICU length of stay.
  • Assessment of physiological parameters such as pulmonary gas exchange and systemic blood flow.

    • Main Results:

    • Maintained spontaneous breathing improves pulmonary gas exchange, systemic blood flow, and tissue oxygen supply.
    • Patients with spontaneous breathing show clinical improvements, including fewer ventilation days, earlier extubation, and shorter ICU stays.
    • Positive effects are documented for specific partial ventilatory support modalities.

    Conclusions:

    • Spontaneous breathing during mechanical ventilation should be maintained in severe pulmonary dysfunction unless contraindicated (e.g., increased intracranial pressure).
    • Partial ventilatory support modalities with documented positive effects can be primary strategies.
    • The traditional approach of controlled mechanical ventilation followed by weaning should be reconsidered.