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Related Experiment Videos

Esophageal involvement in Behcet's disease.

Mohamed Habib Houman1, Imed Ben Ghorbel, Mounir Lamloum

  • 1Department of Internal Medicine, Hospital La Rabta, 1007 Tunis, Tunisia. houman.habib@rns.tn

Yonsei Medical Journal
|September 3, 2002
PubMed
Summary

Esophageal involvement in Behcet

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Area of Science:

  • Gastroenterology
  • Rheumatology
  • Pathology

Background:

  • Behcet's disease is a rare multisystem vasculitis.
  • Esophageal involvement is uncommon, typically presenting as aphthosis or esophagitis.
  • Serious esophageal complications like perforation and stenosis can occur.

Purpose of the Study:

  • To determine the prevalence of esophageal involvement in Behcet's disease.
  • To assess the necessity of routine endoscopy and manometry for Behcet's disease patients.

Main Methods:

  • Prospective study of 23 patients meeting Behcet's disease criteria.
  • Esophagogastroduodenoscopy, esophageal biopsies, and esophageal manometry performed.
  • Disease activity assessed by symptoms and classification.

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Main Results:

  • 14 of 21 patients (excluding those with hiatus hernia) showed abnormalities.
  • Esophageal manometry was abnormal in 35% of cases.
  • Histopathological abnormalities found in 5 of 13 biopsies, including vasculitis in one case.

Conclusions:

  • Esophageal involvement in Behcet's disease is more prevalent than previously thought, even in asymptomatic individuals.
  • Findings suggest routine endoscopy and manometry may not always be necessary.
  • Observed abnormalities are often non-specific.